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Because many pregnant women who smoke do not report it, using multiple-choice questions to assess smoking status in this group may improve disclosure ().

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In conclusion, in this open-label comparison of varenicline with transdermal NRT, varenicline appeared to be safe and well tolerated.

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Even if you have already stopped smoking by this time, your doctor may tell you to take this medicine for 12 more weeks to help you keep off smoking.

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Severity of nicotine withdrawal can vary from “wanting” (a mild desire to smoke that is short lived and easily ignored) to “craving” (a stronger urge to smoke that is more persistent and difficult to ignore) or “needing” (an intense and urgent desire to smoke that is unpleasant and unremitting).

Still, this anticipated future explosion of psychiatric medications will undoubtedly increase the frequency and complexity of polypharmacy and thus further heighten the potential for DDIs and the need for prescribers to be knowledgeable about this issue for years to come.

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It may seem obvious that nicotine in the absence of combustion products is safer than smoking, but the complex metabolism of pregnancy, and systemic response to changes in smoking behaviors during pregnancy are not well enough understood to apply findings from studies in non-pregnant adults to pregnant women.

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Mocking and colleagues studied the effects of varenicline on emotional and cognitive processing in 21 healthy adult non-smokers and concluded that it did not cause problems in emotional processing or impulsivity, providing less support for a possible depressogenic effect of varenicline.

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Morris was supported, in part, by grants from the University of California, San Francisco, Smoking Cessation Leadership Center, and Colorado Department of Public Health and Environment.

Despite these facts, the package insert warns against the use of asenapine in combination with other drugs known to prolong the QTc including Class IA antiarrhythmics (eg, quinidine, procainamide) or Class III antiarrhythmics (eg, amiodarone, sotalol), and an antipsychotic known to prolong the QTc (eg, chlorpromazine, thioridazine, ziprasidone).

This drug interacts with a number of other medicinal compounds.

The present trial was designed to compare varenicline alone with a combination of varenicline and nicotine patch in effects on urges to smoke, and abstinence for up to four weeks.

Patients with COPD have airway obstruction, and they cannot fully empty their lungs before they need to take another breath.

This article reviews literature regarding the safety of smoking-cessation aid varenicline for patients with mental illness.

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